000 04037nam a22005295i 4500
001 978-3-642-30406-4
003 DE-He213
005 20140220083318.0
007 cr nn 008mamaa
008 120823s2012 gw | s |||| 0|eng d
020 _a9783642304064
_9978-3-642-30406-4
024 7 _a10.1007/978-3-642-30406-4
_2doi
050 4 _aQH491
072 7 _aPSC
_2bicssc
072 7 _aSCI072000
_2bisacsh
082 0 4 _a571.8
_223
100 1 _aKubiak, Jacek Z.
_eeditor.
245 1 0 _aMouse Development
_h[electronic resource] :
_bFrom Oocyte to Stem Cells /
_cedited by Jacek Z. Kubiak.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2012.
300 _aVIII, 438 p. 64 illus., 43 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v55
505 0 _aPost-transcriptional control of gene expression during mouse oogenesis -- Polarity and asymmetry during mouse oogenesis and oocyte maturation -- Chromatin Structure and ATRX Function in Mouse Oocytes -- Cyclin B in mouse oocytes and embryos: importance for human reproduction and aneuploidy -- Src protein kinases in mouse and rat oocytes and embryos -- Gradual meiosis-to-mitosis transition in the early mouse embryo -- Maternal control of mouse preimplantation development -- Preimplantation mouse embryo: developmental fate and potency of blastomeres -- Creation of trophectoderm, the first epithelium, in mouse preimplantation development -- Cell Lineage Allocation within the Inner Cell Mass of the Mouse Blastocyst -- Formation of distinct cell types in the mouse blastocyst -- Cell Movements in the Egg Cylinder Stage Mouse Embryo -- Balancing the Dose in the Mouse -- Mouse Oviduct Development -- Cell Lineages, Growth and Repair of the Mouse Heart -- Cellular reprogramming during mouse development -- Differentiation of Definitive Endoderm from Mouse Embryonic Stem Cells -- Mouse and human pluripotent stem cells and the means of their myogenic differentiation -- Stem cells and corneal epithelial maintenance – insights from the mouse and other animal models -- Mouse induced pluripotent stem cells -- Aging in the mouse and perspectives of rejuvenation through induced pluripotent stem cells (iPSCs).
520 _aThe mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) Matthew Kaufman, and Gail Martin. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.
650 0 _aLife sciences.
650 0 _aMedical genetics.
650 0 _aMedicine.
650 0 _aCytology.
650 0 _aStem cells.
650 0 _aDevelopmental biology.
650 1 4 _aLife Sciences.
650 2 4 _aDevelopmental Biology.
650 2 4 _aStem Cells.
650 2 4 _aCell Biology.
650 2 4 _aGene Function.
650 2 4 _aMolecular Medicine.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642304057
830 0 _aResults and Problems in Cell Differentiation,
_x0080-1844 ;
_v55
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-30406-4
912 _aZDB-2-SBL
999 _c103173
_d103173