000			02922nam a22004695i 4500
001			978-3-642-25740-7
003			DE-He213
005			20140220083306.0
007			cr nn 008mamaa
008			120604s2012 gw | s |||| 0|eng d
020			_a9783642257407 _9978-3-642-25740-7
024	7		_a10.1007/978-3-642-25740-7 _2doi
050		4	_aQD433-436
072		7	_aPSB _2bicssc
072		7	_aSCI007000 _2bisacsh
082	0	4	_a572.84 _223
100	1		_aLeontis, Neocles. _eeditor.
245	1	0	_aRNA 3D Structure Analysis and Prediction _h[electronic resource] / _cedited by Neocles Leontis, Eric Westhof.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2012.
300			_aX, 400 p. 115 illus., 80 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aNucleic Acids and Molecular Biology, _x0933-1891 ; _v27
505	0		_aRNA Polymerases and Transcription Factors of Trypanosomes -- SL RNA biogenesis in kinetoplastids: a long and winding road -- Pre-mRNA splicing in Trypanosoma brucei: factors, mechanisms, and regulation -- mRNA turnover in trypanosomes -- tRNA biogenesis and processing -- rRNA biogenesis in trypanosomes -- RNA Editing in African Trypanosomes – a User’s Guide -- The RNA Interference Pathway in Trypanosoma brucei -- Translation in trypanosomatids -- Mitochondrial translation in trypanosomatids -- RNA-Seq analysis of the transcriptome of Trypanosoma brucei.
520			_aWith the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.
650		0	_aLife sciences.
650		0	_aBiochemistry.
650		0	_aNucleic acids.
650	1	4	_aLife Sciences.
650	2	4	_aNucleic Acid Chemistry.
650	2	4	_aBiochemistry, general.
700	1		_aWesthof, Eric. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783642257391
830		0	_aNucleic Acids and Molecular Biology, _x0933-1891 ; _v27
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-642-25740-7
912			_aZDB-2-SBL
999			_c102476 _d102476