000 03357nam a22005055i 4500
001 978-3-642-21858-3
003 DE-He213
005 20140220083258.0
007 cr nn 008mamaa
008 120109s2012 gw | s |||| 0|eng d
020 _a9783642218583
_9978-3-642-21858-3
024 7 _a10.1007/978-3-642-21858-3
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
100 1 _aLara, Jr., Primo N.
_eeditor.
245 1 0 _aKidney Cancer
_h[electronic resource] :
_bPrinciples and Practice /
_cedited by Primo N. Lara, Jr., Eric Jonasch.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2012.
300 _aVIII, 301p. 49 illus., 36 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aEpidemiology and biology: Rencal cell cancer (RCC) epidemiology. Pathology of RCC. Molecular biology of RCC. Prognostic and predictive biomarkers -- Clinical considerations: Clinical presentation and staging -- Surgical and local control modalities: Surgical approaches to early stage RCC. Palliative debulking nephrectomy in advanced stage RCC. Metastasectomy. Energy ablative techniques in RCC. Radiation therapy in RCC -- Systemic therapy considerations: Cytokines and other immune therapies in RCC. Anti-VEGF therapy in RCC. The role of mTOR inhibitors and PI3K pathway blockade in RCC. Sequential versus combination strategies. Presurgical therapy. Toxicity management for patients on targeted therapy. Emerging agents in RCC.
520 _aKidney Cancer: Principles and Practice is an interdisciplinary textbook that encompasses all clinically relevant aspects of the disease and is designed to be as user-friendly as possible in order to meet the needs of the busy practitioner. To this end, the informative text is complemented by helpful boxed sections that present essential ‘take home’ points and patient-oriented cases demonstrating the clinical application of elements discussed in the chapter in question. Original high-quality images, some in color, are included whenever necessary to simplify particularly complex material. The authors are an international group of acknowledged experts in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others. This clinically oriented volume will be of great interest to clinicians, researchers, residents, and fellows, as well as to students and knowledgeable lay people.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aInternal medicine.
650 0 _aCancer
_xSurgery.
650 0 _aPathology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aSurgical Oncology.
650 2 4 _aCancer Research.
650 2 4 _aInternal Medicine.
650 2 4 _aPathology.
700 1 _aJonasch, Eric.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642218576
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-21858-3
912 _aZDB-2-SME
999 _c102005
_d102005