000 03167nam a22004815i 4500
001 978-1-61779-615-9
003 DE-He213
005 20140220083251.0
007 cr nn 008mamaa
008 120403s2012 xxu| s |||| 0|eng d
020 _a9781617796159
_9978-1-61779-615-9
024 7 _a10.1007/978-1-61779-615-9
_2doi
050 4 _aRB1-214
072 7 _aMMF
_2bicssc
072 7 _aMED067000
_2bisacsh
082 0 4 _a616.07
_223
100 1 _aBologna, Mauro.
_eeditor.
245 1 0 _aBiotargets of Cancer in Current Clinical Practice
_h[electronic resource] /
_cedited by Mauro Bologna.
264 1 _aTotowa, NJ :
_bHumana Press,
_c2012.
300 _aXVI, 563p. 100 illus., 57 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Clinical Pathology
505 0 _aCentral Nervous System Tumors -- Head and Neck Tumors -- Thyroid Cancer -- Targeted Therapies for Non-Small Cell Lung Cancer -- Non-Hodgkin Lymphomas -- Leukemias -- Breast Cancer -- Esophago-Gastric Cancer -- Colorectal Cancer -- Hepatocellular Carcinoma -- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma -- Bladder Cancer -- Biomarkers in Prostate cancer -- Ovarian Cancer -- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer -- Biotargets in Sarcomas: The Past, Present and a Look into the Future -- Melanoma and other skin cancers -- Molecular pathology of cancer metastasis: suggestions for future therapy -- Current and future developments in cancer therapy research: miRNAs as new promising targets or tools.
520 _aBiotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
650 0 _aMedicine.
650 0 _aMedical laboratories.
650 0 _aOncology.
650 0 _aPathology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aPathology.
650 2 4 _aOncology.
650 2 4 _aLaboratory Medicine.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781617796142
830 0 _aCurrent Clinical Pathology
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-61779-615-9
912 _aZDB-2-SME
999 _c101612
_d101612