000 04146nam a22005535i 4500
001 978-1-60761-561-3
003 DE-He213
005 20140220083251.0
007 cr nn 008mamaa
008 111129s2012 xxu| s |||| 0|eng d
020 _a9781607615613
_9978-1-60761-561-3
024 7 _a10.1007/978-1-60761-561-3
_2doi
050 4 _aRC648-665.2
072 7 _aMJG
_2bicssc
072 7 _aMED027000
_2bisacsh
082 0 4 _a616.4
_223
100 1 _aDiamanti-Kandarakis, Evanthia.
_eeditor.
245 1 0 _aEndocrine Disruptors and Puberty
_h[electronic resource] /
_cedited by Evanthia Diamanti-Kandarakis, Andrea C. Gore.
250 _a1.
264 1 _aTotowa, NJ :
_bHumana Press,
_c2012.
300 _aXVII, 378p. 18 illus., 11 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aContemporary Endocrinology
505 0 _aIntroduction to endocrine disruptors and Puberty -- In utero exposure to environmental chemicals - Lessons from maternal cigarette smoking and its effects on gonad development and puberty -- Reproductive Neuroendocrine Targets of Developmental Exposure to Endocrine Disruptors -- Endocrine disruptors and puberty disorders from mice to men (and women) -- Thyroid hormone regulation of mammalian reproductive development and the potential impact of endocrine disrupting chemicals -- Developmental exposure to endocrine disruptors and ovarian function -- Developmental exposure to environmental endocrine disruptors and adverse effects on mammary gland development -- Developmental exposure to endocrine disruptors and male urogenital tract malformations -- EDC exposures and the development of reproductive and non-reproductive behaviors -- Adipocytes as target cells for endocrine disruption -- Altered Glucose Homeostasis Resulting From Developmental Exposures To Endocrine Disruptors -- Developmental Exposure to Endocrine Disrupting Chemicals: Is there a Connection with Birth and Childhood Weights? -- The Impact Of Endocrine Disruptors On Female Pubertal Timing -- The influence of endocrine disruptors on Male Pubertal Timing -- Secular Trends in Pubertal Timing: A Role for Environmental Chemical Exposure?.
520 _aEndocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole.  Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge.  In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors.  Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem.  An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions. 
650 0 _aMedicine.
650 0 _aToxicology.
650 0 _aInternal medicine.
650 0 _aEndocrinology.
650 0 _aOncology.
650 0 _aCytology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aEndocrinology.
650 2 4 _aOncology.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aCell Biology.
650 2 4 _aInternal Medicine.
700 1 _aGore, Andrea C.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781607615606
830 0 _aContemporary Endocrinology
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-60761-561-3
912 _aZDB-2-SME
999 _c101565
_d101565