| 000 | 02589nam a22004575i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4614-5404-5 | ||
| 003 | DE-He213 | ||
| 005 | 20140220083250.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 130217s2012 xxu| s |||| 0|eng d | ||
| 020 |
_a9781461454045 _9978-1-4614-5404-5 |
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| 024 | 7 |
_a10.1007/978-1-4614-5404-5 _2doi |
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| 050 | 4 | _aQR180-189.5 | |
| 072 | 7 |
_aMJCM _2bicssc |
|
| 072 | 7 |
_aMED044000 _2bisacsh |
|
| 082 | 0 | 4 |
_a616.079 _223 |
| 100 | 1 |
_aEmbers, Monica E. _eeditor. |
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| 245 | 1 | 4 |
_aThe Pathogenic Spirochetes: strategies for evasion of host immunity and persistence _h[electronic resource] / _cedited by Monica E. Embers. |
| 264 | 1 |
_aBoston, MA : _bSpringer US : _bImprint: Springer, _c2012. |
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| 300 |
_aXVI, 265 p. 49 illus., 46 illus. in color. _bonline resource. |
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| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 347 |
_atext file _bPDF _2rda |
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| 505 | 0 | _aTreponema pallidum -- Immunoseclusion and Chronic Infection -- Treponema Denticola -- Borrelial Complement-binding Proteins -- Treponema Pallidum Repeat (tpr) Genes and Antigenic Variation -- Antigenic Variation of V1sE by Borrelia Burgdorferi -- Modulation of Cytokine Signaling by Borrelia Burgdorferi -- Leptospira: Invasion, Pathogenesis and Persistence -- Immune Resistance by Relapsing Fever Spirochetes -- Neuroborreliosis Caused by Borrelia Burgdorferi: Possible Role of Glial Cells -- Antibiotic Resistance in Treponema Pallidum subsp. Pallidum, the Syphilis Agent -- Borrelia Burgdorferi Persistence Post-Antibiotic Treatment. | |
| 520 | _aThis book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites. It also explores antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation. | ||
| 650 | 0 | _aMedicine. | |
| 650 | 0 | _aImmunology. | |
| 650 | 0 | _aMonoclonal antibodies. | |
| 650 | 0 | _aMicrobiology. | |
| 650 | 1 | 4 | _aBiomedicine. |
| 650 | 2 | 4 | _aImmunology. |
| 650 | 2 | 4 | _aAntibodies. |
| 650 | 2 | 4 | _aMedical Microbiology. |
| 710 | 2 | _aSpringerLink (Online service) | |
| 773 | 0 | _tSpringer eBooks | |
| 776 | 0 | 8 |
_iPrinted edition: _z9781461454038 |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4614-5404-5 |
| 912 | _aZDB-2-SBL | ||
| 999 |
_c101532 _d101532 |
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