000			04608nam a22005175i 4500
001			978-1-4614-3360-6
003			DE-He213
005			20140220083247.0
007			cr nn 008mamaa
008			120621s2012 xxu| s |||| 0|eng d
020			_a9781461433606 _9978-1-4614-3360-6
024	7		_a10.1007/978-1-4614-3360-6 _2doi
050		4	_aRC254-282
072		7	_aMJCL _2bicssc
072		7	_aMED062000 _2bisacsh
082	0	4	_a616.994 _223
100	1		_aSupino, Phyllis G. _eeditor.
245	1	0	_aPrinciples of Research Methodology _h[electronic resource] : _bA Guide for Clinical Investigators / _cedited by Phyllis G. Supino, Jeffrey S. Borer.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2012.
300			_aXVI, 276 p. 55 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPreface -- Foreword -- Overview of the Research Process -- Developing a Research Problem -- The Research Hypothesis: Role and Construction -- Design and Interpretation of Observational Studies: Cohort, Case-Control and Cross-Sectional Designs -- Fundamental Issues in Evaluating the Impact of Interventions: Sources and Control of Bias -- Protocol Development and Preparation for a Clinical Trial -- Data Collection and Management in Clinical Research -- Constructing and Evaluating Self Report Measures.- Selecting and Evaluating Secondary Data: The Role of Systematic Reviews and Meta-Analysis -- Sampling Methodology: Implications for Drawing Conclusions from Clinical Research Findings -- Introductory Statistics in Medical Research -- Ethical Issues in Clinical Research -- How to Prepare a Scientific Paper.
520			_aPrinciples of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.
650		0	_aMedicine.
650		0	_aInternal medicine.
650		0	_aCardiology.
650		0	_aEndocrinology.
650		0	_aNeurology.
650		0	_aOncology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aOncology.
650	2	4	_aCardiology.
650	2	4	_aInternal Medicine.
650	2	4	_aEndocrinology.
650	2	4	_aNeurology.
700	1		_aBorer, Jeffrey S. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461433590
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-3360-6
912			_aZDB-2-SME
999			_c101349 _d101349