000 04540nam a22004815i 4500
001 978-1-4614-0751-5
003 DE-He213
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007 cr nn 008mamaa
008 111026s2012 xxu| s |||| 0|eng d
020 _a9781461407515
_9978-1-4614-0751-5
024 7 _a10.1007/978-1-4614-0751-5
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
100 1 _aGutkin, Boris.
_eeditor.
245 1 0 _aComputational Neuroscience of Drug Addiction
_h[electronic resource] /
_cedited by Boris Gutkin, Serge H. Ahmed.
250 _a1.
264 1 _aNew York, NY :
_bSpringer New York,
_c2012.
300 _aXIV, 342 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series in Computational Neuroscience ;
_v10
505 0 _aForeword: P Dayan -- Part 1 – Pharmacological-based models of addiction -- Chapter 1. Simple deterministic mathematical Model of maintained drug delf-Administration behavior and its pharmacological applications. V.L. Tsibulsky* and A.B. Norman -- Chapter 2. Intermittent Adaptation : A mathematical model of drug tolerance, dependence and addiction. A. Peper -- Chapter 3. Control theory and addictive behavior. D. Newlin, P.A. Regalia, T.I. Seidman, G. Bobashev -- Part 2 – Neurocomputational models of addiction -- Chapter 4. Circuit models of addiction: receptors and neural dynamics in nicotine self-administration. M. Graupner and B. Gutkin -- Chapter 5. N Dual-system learning models and drugs of abuse. N.D. Daw and D.A. Simon -- Chapter 6. Modeling decision-making systems in addiction. Z. Kurth-Nelson and A. D. Redish -- Chapter 7. Computational models of incentive-sensitization in addiction: Dynamic limbic transformation of learning into motivation. J. Zhang, K. C. Berridge, and J. W. Aldridge -- Chapter 8.  Understanding addiction as a pathological state of multiple decision making processes: a neurocomputational perspective. M. Keramati, A. Dezfouli and P. Piray -- Part 3 – Economic-based models of addiction -- Chapter 9. Policies and priors. K Friston -- Chapter 10. Toward a Computationally Unified Behavioral-Economic Model of Addiction. E.T. Mueller, L.P. Carter and W.K. Bickel -- Chapter 11. Simulating Patterns of Heroin Addiction within the Social Context of a Local Heroin Market. L. Hoffer, G. Bobashev and R. J Morris.
520 _aDrug addiction is one of the most important public health problems in Western societies, and is a rising concern for developing nations. Over the past three decades, experimental research on the neurobiology and psychology of drug addiction has generated a tremendous amount of exciting data, from the molecular to the behavioral levels. As a result, a new and pressing challenge for addiction research is to formulate a synthetic theoretical framework that goes well beyond mere scientific eclecticism to deepen our understanding of drug addiction and to foster our capacity to prevent and to cure drug addiction. Recently, researchers from a broad spectrum of scientific disciplines – from pharmacokinetics to neuroeconomics – have begun to take up this challenge. Computational Neuroscience of Drug Addiction collects recent mathematical and neurocomputational modeling approaches to drug self-administration and addiction. This selection of chapters illustrates how mathematical modeling can contribute to our understanding of the mechanisms underlying the transition between the different stages of addiction, from initiation of regulated drug use and subsequent loss of control over drug use to relapse after long-term abstinence. The volume provides an overview of this emerging area and will serve as a standard reference for addiction researchers and quantitative scientists entering the field.  
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aBiology
_xData processing.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aComputer Appl. in Life Sciences.
700 1 _aAhmed, Serge H.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461407508
830 0 _aSpringer Series in Computational Neuroscience ;
_v10
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-0751-5
912 _aZDB-2-SBL
999 _c100919
_d100919