000			03673nam a22004095i 4500
001			978-0-85729-950-5
003			DE-He213
005			20140220083229.0
007			cr nn 008mamaa
008			111003s2012 xxk| s |||| 0|eng d
020			_a9780857299505 _9978-0-85729-950-5
024	7		_a10.1007/978-0-85729-950-5 _2doi
050		4	_aRC927-927.5
072		7	_aMJM _2bicssc
072		7	_aMED083000 _2bisacsh
082	0	4	_a616.723 _223
100	1		_aEbringer, Alan. _eauthor.
245	1	0	_aRheumatoid Arthritis and Proteus _h[electronic resource] / _cby Alan Ebringer.
264		1	_aLondon : _bSpringer London, _c2012.
300			_aX, 233p. 53 illus., 2 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aScope and Distribution of the RA Problem -- History of the Attempts to Find the Cause of RA -- HLA-DR1/4 and Antibodies to Proteus in London -- Antibodies to Proteus in Irish patients with rheumatoid arthritis -- Antibodies to Proteus in rheumatoid arthritis patients from Bermuda and from Hertfordshire in England -- Antibodies to Proteus in rheumatoid arthritis patients from Brest and Toulouse in France -- Dutch patients with rheumatoid arthritis have antibodies to Proteus -- Anti-Proteus antibodies in Norwegian rheumatoid arthritis patients following a lactovegetarian diet -- Antibodies to Proteus in rheumatoid arthritis patients from Norway, Spain and England -- Antibodies to Proteus in rheumatoid arthritis  patients from southern Japan -- Urine Cultures and Correlation -- Molecular similarity between the “shared epitope” of rheumatoid arthritis and bacteria -- The “shared epitope”, Proteus haemolysin, XI collagen and rheumatoid arthritis -- Gram-negative bacteria possess sequences which resemble the “shared epitope”but only Proteus infect rheumatoid arthritis patients -- Immune responses to Proteus in rheumatoid arthritis patients from Finland and Japan -- Molecular similarity between the rheumatoid arthritis associated motif EQKRAA and structurally related sequences of  Proteus -- Rheumatoid arthritis sera are cytotoxic to cells bearing HLA and collagen susceptibility sequences -- The scientific method of Sir Karl Popper. Rheumatoid arthritis and “Popper sequences”.
520			_aRheumatoid Arthritis and Proteus explores the idea that Rheumatoid arthritis is caused by a urinary tract infection as a result of Proteus bacteria. Rheumatoid arthritis is a severe, painful and crippling disease affecting millions of people throughout the world, especially women. Genetic studies over the last 30 years have shown that individuals who possess the white cell blood groups HLA-DR1/4 carry a susceptibility sequence and are more likely to develop the disease.   This book uses the methods of Sir Karl Popper, the philosopher of science, to present 12 “Popper sequences” which have been identified to indicate that Proteus is the causative agent of Rheumatoid Arthritis. Rheumatoid Arthritis and Proteus proposes that Anti-Proteus therapies should be followed as early as possible to prevent the crippling and irreversible joint deformities that occur in Rheumatoid Arthritis.
650		0	_aMedicine.
650		0	_aRheumatology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aRheumatology.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780857299499
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-85729-950-5
912			_aZDB-2-SME
999			_c100295 _d100295