000			03857nam a22004935i 4500
001			978-0-85729-920-8
003			DE-He213
005			20140220083229.0
007			cr nn 008mamaa
008			111118s2012 xxk| s |||| 0|eng d
020			_a9780857299208 _9978-0-85729-920-8
024	7		_a10.1007/978-0-85729-920-8 _2doi
050		4	_aRC681-688.2
072		7	_aMJD _2bicssc
072		7	_aMED010000 _2bisacsh
082	0	4	_a616.12 _223
100	1		_aAbraham, David. _eeditor.
245	1	0	_aTranslational Vascular Medicine _h[electronic resource] : _bPathogenesis, Diagnosis, and Treatment / _cedited by David Abraham, Clive Handler, Michael Dashwood, Gerry Coghlan.
264		1	_aLondon : _bSpringer London, _c2012.
300			_aXIV, 266p. 54 illus., 28 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aSection 1 – Hot Topics in Vascular Biology -- 1. Pericytes: Adaptable vascular progenitors -- 2. Benefits and risks of manipulating the HIF hydroxylase pathway in ischaemic heart disease -- 3. Cytoprotective mechanisms in the vasculature -- 4. Notch signalling in vascular development -- Section 2 - Novel Molecular Mediators Regulating Cardiovascular System -- 5. The therpeutic potential of dimethylarginine dimethylaminohydrolase mediated regulation of nitric oxide synthesis. -- 6. Potassium channels regulating the electrical activity of the heart -- 7. Free radicals oxidant stress and cardiovascular disease -- Section 3 - Clinical Aspects of Cardiovascular Disease -- 8. The Broken Heart Syndrome -- 9. Lymphatic endothelium in health and disease -- 10. Importance of sub-type selectivity for endothelin receptor antagonists in the human vasculature -- 11. Non-pharmacological treatment of PAD -- 12. Surgical Approaches to Abdominal Aortic Aneurysm Repair -- Section 4 - Clinical and translational Aspects of Pulmonary Vascular Disease -- 13. Understanding the pathobiology of pulmonary vascular disease -- 14. Inflammation in pulmonary arterial hypertension.
520			_aModern medicine is increasingly focused on integrating the results of basic scientific research and clinical research, “translational medicine” to provide improved patient care. This collaborative approach which is a “two way street” has proven very useful in various fields in cardiovascular medicine.     Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment provides extensive information on new and exciting advances in such topics as surgery and non-pharmacological treatments for atherosclerotic disease of the aorta, pulmonary arterial hypertension, cytoprotective mechanisms in the vasculature, and the “Broken Heart Syndrome”. The Editors and their expert panel of contributors have explored the bi-directional and integrated approaches of translational cardiovascular medicine, linking basic science to patient care.   This book is a highly useful method to understand these complex topics and provides considerable insight into important areas of translational cardiovascular medicine and key bibliographies for the reader.
650		0	_aMedicine.
650		0	_aGene expression.
650		0	_aHuman physiology.
650		0	_aCardiology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aCardiology.
650	2	4	_aGene Expression.
650	2	4	_aHuman Physiology.
700	1		_aHandler, Clive. _eeditor.
700	1		_aDashwood, Michael. _eeditor.
700	1		_aCoghlan, Gerry. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780857299192
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-85729-920-8
912			_aZDB-2-SME
999			_c100290 _d100290