Library Services | Technical University of Kenya

Your cart is empty.
Normal view MARC view ISBD view

Coarse-Grained Modelling of DNA and DNA Self-Assembly [electronic resource] / by Thomas E. Ouldridge.

By: Ouldridge, Thomas E [author.].
Contributor(s): SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Springer Theses, Recognizing Outstanding Ph.D. Research: Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012Description: XI, 176 p. 44 illus., 25 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783642305177.Subject(s): Physics | Polymers | Nanotechnology | Physics | Biophysics and Biological Physics | Nanotechnology | Polymer Sciences | Statistical Physics, Dynamical Systems and Complexity | Soft and Granular Matter, Complex Fluids and MicrofluidicsDDC classification: 571.4 Online resources: Click here to access online
Contents:
A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker.
In: Springer eBooksSummary: This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Tags from this library: No tags from this library for this title. Log in to add tags.
No physical items for this record

A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker.

This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.

There are no comments for this item.

Log in to your account to post a comment.

2017 | The Technical University of Kenya Library | +254(020) 2219929, 3341639, 3343672 | library@tukenya.ac.ke | Haile Selassie Avenue