Session 1. Modeling and Simulation of Biological Processes -- A Formal Model for Gene Regulatory Networks with Time Delays -- Modelling fim Expression in Escherichia Coli K12 -- Study of the Structural Pathology Caused by CYP2C9 Polymorphisms towards Flurbiprofen Metabolism Using Molecular Dynamics Simulation -- 3D Structure Modeling of a Transmembrane Protein, Fatty Acid Elongase -- Session 2. Gene Expression Analysis -- Sequential Application of Feature Selection and Extraction for Predicting Breast Cancer Aggressiveness -- On Assigning Individuals from Cryptic Population Structures to Optimal Predicted Subpopulations: An Empirical Evaluation of Non-parametric Population Structure Analysis Techniques -- Extended Constraint-Based Boolean Analysis: A Computational Method in Genetic Network Inference -- Mining LINE-1 Characteristics That Mediate Gene Expression -- Session 3. Biological Sequence Analysis and Network Reconstruction -- Mining Regulatory Elements in Non-coding Regions of Arabidopsis thaliana -- Prediction of Non-coding RNA and Their Targets in Spirulina platensis Genome -- Reconstruction of Starch Biosynthesis Pathway in Cassava Using Comparative Genomic Approach -- Session 4. Bio-data Visualization and Biological Databases -- Catalog of Genetic Variations (SNPs and CNVs) and Analysis Tools for Thai Genetic Studies -- The Genome Atlas Resource -- INVERTER: INtegrated Variable numbER Tandem rEpeat findeR -- Design of an Enterobacteriaceae Pan-Genome Microarray Chip -- Session 5. Medical and Biomedical Informatics -- Multi-objective Particle Swarm Optimisation for Phase Specific Cancer Drug Scheduling -- A Vaccine Strategy for Plant Allergy by RNA Interference – An in Silico Approach -- Unsupervised Algorithms for Population Classification and Ancestry Informative Marker Selection -- Genome-Based Screening for Drug Targets Identification: Application to Typhoid Fever.

This book constitutes the refereed proceedings of the First International Conference on Computational Systems-Biology and Bioinformatics, CSBio 2010, held in Bangkok, Thailand, in November 2010. The 19 revised full papers presented were carefully reviewed and selected from a total of 48 submissions. The papers cover a wide range of topics and are organized in five topical sections on modeling and simulation of biological processes, gene expression analysis, biological sequence analysis and network reconstruction, bio-data visualization and biological databases, as well as medical and biomedical informatics.