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Lead-Seeking Approaches [electronic resource] / edited by Matthew M. Hayward.

By: Hayward, Matthew M [editor.].
Contributor(s): SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Topics in Medicinal Chemistry: 5Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2010Description: XIII, 217p. 36 illus., 10 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783642010750.Subject(s): Chemistry | Neurosciences | Chemistry, Organic | Biochemistry | Chemistry | Medicinal Chemistry | Neurosciences | Organic ChemistryDDC classification: 615.19 Online resources: Click here to access online
Contents:
Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery -- Lead Identification -- Lead Discovery Using Virtual Screening -- Overview of Hit to Lead: The Medicinal Chemist's Role from HTS Retest to Lead Optimization Hand Off -- NMR Spectroscopy in Fragment Based Drug Design -- High Throughput Screening in the Twenty-First Century.
In: Springer eBooksSummary: Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design Kevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery John W. Ellingboe • Adam M. Gilbert: Lead Identification
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Hit Triage: Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery -- Lead Identification -- Lead Discovery Using Virtual Screening -- Overview of Hit to Lead: The Medicinal Chemist's Role from HTS Retest to Lead Optimization Hand Off -- NMR Spectroscopy in Fragment Based Drug Design -- High Throughput Screening in the Twenty-First Century.

Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design Kevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery John W. Ellingboe • Adam M. Gilbert: Lead Identification

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