Phosphoinositide 3-kinase in Health and Disease [electronic resource] : Volume 2 / edited by Christian Rommel, Bart Vanhaesebroeck, Peter K. Vogt.
By: Rommel, Christian [editor.].
Contributor(s): Vanhaesebroeck, Bart [editor.] | Vogt, Peter K [editor.] | SpringerLink (Online service).
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BookSeries: Current Topics in Microbiology and Immunology: 347Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2011Description: X, 306 p. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9783642148163.Subject(s): Medicine | Oncology | Biomedicine | Cancer ResearchDDC classification: 614.5999 Online resources: Click here to access online
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Springer eBooksSummary: From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here the authors give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here
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From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here the authors give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here
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