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Kainate Receptors [electronic resource] : Novel Signaling Insights / edited by Antonio Rodríguez-Moreno, Talvinder S. Sihra.

By: Rodríguez-Moreno, Antonio [editor.].
Contributor(s): Sihra, Talvinder S [editor.] | SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Advances in Experimental Medicine and Biology: 717Publisher: Boston, MA : Springer US, 2011Description: XX, 131 p. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9781441995575.Subject(s): Medicine | Biomedicine | Biomedicine general | Molecular MedicineDDC classification: 610 Online resources: Click here to access online
Contents:
Metabotropic Actions of Kainate Receptors in the Control of GABA Release -- In the Developing Hippocampus Kainate Receptors Control the Release of GABA from Mossy Fiber Terminals via a Metabotropic Type of Action -- Localization and Functions of Kainate Receptors in the Basal Ganglia -- Metabotropic Actions of Kainate Receptors in the Control of Glutamate Release in the Hippocampus -- Metabotropic Actions of Kainate Receptors in the Regulation of IsAHP and Excitability in CA1 Pyramidal Cells -- Kainate Receptors with a Metabotropic Signature Enhance Hippocampal Excitability by Regulating the Slow After‑Hyperpolarization in CA3 Pyramidal Neurons -- Metabotropic Actions of Kainate Receptors in Dorsal Root Ganglion Cells -- Role of Kainate Receptors in Network Activity during Development -- Kainate Receptor Modulation by Sodium and Chloride -- BTB‑Kelch Proteins and Ubiquitination of Kainate Receptors.
In: Springer eBooksSummary: This volume critically examines the functional actions of the kainate‑type glutamate receptors (KARs). Following on from the larger body of work on the NMDA‑ and AMPA-type ionotropic glutamate receptors (GluRs), studies with KARs have consistently thrown up exceptions to general rules about synaptic modulation. Contributors herein provide an insight to the idiosyncracies that now almost typify the KAR field. The fascinating insights provided in this volume serve to encourage searching mechanistic questions.
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Metabotropic Actions of Kainate Receptors in the Control of GABA Release -- In the Developing Hippocampus Kainate Receptors Control the Release of GABA from Mossy Fiber Terminals via a Metabotropic Type of Action -- Localization and Functions of Kainate Receptors in the Basal Ganglia -- Metabotropic Actions of Kainate Receptors in the Control of Glutamate Release in the Hippocampus -- Metabotropic Actions of Kainate Receptors in the Regulation of IsAHP and Excitability in CA1 Pyramidal Cells -- Kainate Receptors with a Metabotropic Signature Enhance Hippocampal Excitability by Regulating the Slow After‑Hyperpolarization in CA3 Pyramidal Neurons -- Metabotropic Actions of Kainate Receptors in Dorsal Root Ganglion Cells -- Role of Kainate Receptors in Network Activity during Development -- Kainate Receptor Modulation by Sodium and Chloride -- BTB‑Kelch Proteins and Ubiquitination of Kainate Receptors.

This volume critically examines the functional actions of the kainate‑type glutamate receptors (KARs). Following on from the larger body of work on the NMDA‑ and AMPA-type ionotropic glutamate receptors (GluRs), studies with KARs have consistently thrown up exceptions to general rules about synaptic modulation. Contributors herein provide an insight to the idiosyncracies that now almost typify the KAR field. The fascinating insights provided in this volume serve to encourage searching mechanistic questions.

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