Neuroblastoma [electronic resource] : Diagnosis, Therapy, and Prognosis / edited by M.A. Hayat.
By: Hayat, M.A [editor.].
Contributor(s): SpringerLink (Online service).
Material type:
BookSeries: Pediatric Cancer: 1Publisher: Dordrecht : Springer Netherlands, 2012Description: XVIII, 262p. 40 illus., 24 illus. in color. online resource.Content type: text Media type: computer Carrier type: online resourceISBN: 9789400724181.Subject(s): Medicine | Oncology | Radiology, Medical | Pediatrics | Surgery | Biomedicine | Cancer Research | Pediatrics | Diagnostic Radiology | Pediatric SurgeryDDC classification: 614.5999 Online resources: Click here to access online
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Springer eBooksSummary: Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
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