Computational Modeling in Tissue Engineering (Record no. 97264)

000 -LEADER
fixed length control field 05120nam a22004695i 4500
001 - CONTROL NUMBER
control field 978-3-642-32563-2
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220082853.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 121030s2013 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783642325632
-- 978-3-642-32563-2
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-3-642-32563-2
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number R856-857
072 #7 - SUBJECT CATEGORY CODE
Subject category code MQW
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code TEC009000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610.28
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Geris, Liesbet.
Relator term editor.
245 10 - TITLE STATEMENT
Title Computational Modeling in Tissue Engineering
Medium [electronic resource] /
Statement of responsibility, etc edited by Liesbet Geris.
264 #1 -
-- Berlin, Heidelberg :
-- Springer Berlin Heidelberg :
-- Imprint: Springer,
-- 2013.
300 ## - PHYSICAL DESCRIPTION
Extent XI, 442 p. 135 illus., 37 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
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-- rdamedia
338 ## -
-- online resource
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-- rdacarrier
347 ## -
-- text file
-- PDF
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490 1# - SERIES STATEMENT
Series statement Studies in Mechanobiology, Tissue Engineering and Biomaterials,
International Standard Serial Number 1868-2006 ;
Volume number/sequential designation 10
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note In vivo, in vitro, in silico:  computational tools for product and process design in tissue engineering -- Protein modeling and surface folding by limiting the degrees of freedom -- Adaptive Quasi-linear Viscoelastic Modeling -- Computational modeling of mass transport and its relation to cell behavior in tissue engineering constructs -- Computational Methods in the Modeling of Scaffolds for Tissue Engineering -- Computational Modeling of Tissue Engineering Scaffolds as Delivery Devices for Mechanical and Mechanically Modulated Signals -- Modeling the cryopreservation process of a suspension of cells: the effect of a sizedistributed cell population -- Mesenchymal Stem Cell Heterogeneity and Ageing in vitro - a Model Approach.-  Image-based cell quality assessment: Modeling of cell morphology and quality for clinical cell therapy -- Continuum modelling of in vitro tissue engineering: a review -- Multiphysics Computational Modeling in Cartilage Tissue Engineering -- Oxygen Transport in Bioreactors for Engineered Vascular Tissues -- Multi-scale Modelling of Vascular Disease: Abdominal Aortic Aneurysm Evolution -- Computational Mechanobiology in Cartilage and Bone Tissue Engineering: From Cell Phenotype to Tissue Structure -- Mechanobiological modelling of angiogenesis impact on tissue engineering and bone regeneration -- Mathematical modeling of regeneration of a tissue-engineered trachea.
520 ## - SUMMARY, ETC.
Summary, etc One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in:  (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling.  The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone.  For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself.  In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Engineering.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedical engineering.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomaterials.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Engineering.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedical Engineering.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biophysics and Biological Physics.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomaterials.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783642325625
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Studies in Mechanobiology, Tissue Engineering and Biomaterials,
-- 1868-2006 ;
Volume number/sequential designation 10
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-642-32563-2
912 ## -
-- ZDB-2-ENG

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