Innate Tolerance in the CNS (Record no. 94494)

000 -LEADER
fixed length control field 06456nam a22005055i 4500
001 - CONTROL NUMBER
control field 978-1-4419-9695-4
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220082803.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781441996954
-- 978-1-4419-9695-4
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4419-9695-4
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC321-580
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSAN
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED057000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612.8
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Gidday, Jeffrey M.
Relator term editor.
245 10 - TITLE STATEMENT
Title Innate Tolerance in the CNS
Medium [electronic resource] :
Remainder of title Translational Neuroprotection by Pre- and Post-Conditioning /
Statement of responsibility, etc edited by Jeffrey M. Gidday, Miguel A. Perez-Pinzon, John H. Zhang.
264 #1 -
-- New York, NY :
-- Springer New York :
-- Imprint: Springer,
-- 2013.
300 ## - PHYSICAL DESCRIPTION
Extent IX, 699 p. 60 illus., 44 illus. in color.
Other physical details online resource.
336 ## -
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-- txt
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-- computer
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-- rdamedia
338 ## -
-- online resource
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347 ## -
-- text file
-- PDF
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490 1# - SERIES STATEMENT
Series statement Springer Series in Translational Stroke Research
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Preface -- Section I.   Comparative Physiology and Historical Background -- 1. Tolerance, Historical Review -- 2. Anoxia resistance in lower and higher vertebrates -- 3. Hibernation:  A Natural Model of Tolerance to Cerebral Ischemia/Reperfusion -- 4. Preconditioning in the Heart -- Section II.   Conditioning Methods -- 5. Neuroprotection and Physical Preconditioning:  Exercise, Hypothermia, and Hyperthermia -- 6. A New Future in Brain Preconditioning Based on Nutraceuticals:  Focus on α-Linolenic Omega-3 Fatty Acids for Stroke Protection -- 7. Medical Gases for Conditioning:  Volatile Anesthetics, Hyperbaric Oxygen, and Hydrogen Sulfide -- 8. Hypoxic Preconditioning in the CNS -- 9. Pharmacologic Preconditioning -- 10. Surgical Methods to Induce Brain Preconditioning -- Section III. Conditioning Models for Cerebral Ischemia -- 11. Tolerance Against Global Cerebral Ischemia:  Experimental Strategies, Mechanisms, and Clinical Applications -- 12. Preconditioning and Neuroprotection in the Immature Brain -- 13. Conditioning Studies in Focal Cerebral Ischemia:  Model Selection, Physiological Monitoring, and Other Methodological Issues -- 14. Preconditioning for Subarachnoid Hemorrhage -- 15. Preconditioning for Intracerebral Hemorrhage -- 16. The Protective Effects of Ischemic Postconditioning in Experimental Stroke -- Section IV. Mechanisms of Preconditioning -- 17. Synaptic Signaling in Ischemic Tolerance -- 18 -- The Genomics of Preconditioning and Ischemic Tolerance -- 19. How do Subcellular Organelles Participate in Preconditioning-Conferred Neuroprotection? -- 20. Ischemic Preconditioning–Mediated Signaling Pathways Lead to Tolerance Against Cerebral Ischemia -- 21. Preconditioning the Neurovascular Unit:  Tolerance in the Brain’s Non-Neuronal Cells -- Section V.   Other Neurological Disorders -- 22. Preconditioning for Surgical Brain Injury -- 23. Intrinsic Neuroprotection in Traumatic Brain Injury -- 24. Preconditioning for Epilepsy -- 25. Ischemic Pre- and Post-Conditioning in the Retina -- Section VI. Clinical Applications -- 26. Clinical Cerebral Ischemic Preconditioning -- 27. Preconditioning Strategy:  Coronary Bypass, Subarachnoid Hemorrhage, Temporary Proximal Vessel Occlusion in Carotid Revascularization, and Intracranial Aneurysm Surgery -- 28. HBO preconditioning for TBI and Stroke Patients -- 29. Electroacupuncture Preconditioning for Stroke Patients -- 30. Clinical Trials of Ischemic Conditioning -- Epilogue -- Index.    .
520 ## - SUMMARY, ETC.
Summary, etc Cerebral ischemia from cardiac arrest, stroke, and subarachnoid and intracerebral hemorrhage, together with trauma, epilepsy, and other CNS pathologies, continue to impose immense burdens of morbidity and mortality the world over. Despite many decades of research aimed at understanding the genetic and molecular basis of these pathologies, therapeutics developed on the basis of blocking ‘known’ injury mechanisms can actually claim few clinical successes. The field of CNS “preconditioning” was born from the preclinical finding more than 20 years ago that intentional activation of innate, cytoprotective factors could provide robust protection, or “tolerance” against cerebral ischemic injury.  Herein, up-to-date summaries on all aspects of preconditioning for CNS disease, including the emerging topics of postconditioning and remote pre- and post-conditioning, are provided by the leading scientists in the field. The translational potential of both preclinical and clinical advances is underscored throughout, with the hope of accelerating the bench-to-bedside success of endogenous cytoprotection as a therapeutic strategy.   Jeffrey M. Gidday PhD, Associate Professor of Neurosurgery at Washington University School of Medicine, has been working in the field of CNS preconditioning for 18 years, and has numerous publications on preconditioning-induced protection in the setting of several different cerebral and retinal pathologies.  Miguel A. Perez-Pinzon PhD is Professor of Neurology/Neuroscience, Vice-Chair for Basic Science of Neurology at the University of Miami Miller School of Medicine. He began studies of ischemic preconditioning in 1995 and for many years prior to that worked in the field of anoxia tolerance, publishing close to 50 peer-reviewed articles and many book chapters on these topics. John H. Zhang MD PhD is Professor of Neurosurgery, Anesthesiology, and Physiology, and Vice-Chair of the Basic Science Department at the Loma Linda University School of Medicine. His research interests include stroke and medical gases, and he has published papers related to pre-, post- and remote-conditioning in subarachnoid hemorrhage, focal cerebral ischemia, and neonatal brain injury.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurosciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurobiology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurosciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurobiology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Perez-Pinzon, Miguel A.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, John H.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781441996947
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Springer Series in Translational Stroke Research
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4419-9695-4
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