Pharmaceutical biocatalysis : (Record no. 129655)

000 -LEADER
fixed length control field 03782cam a22006371i 4500
001 - CONTROL NUMBER
control field 9781003045397
003 - CONTROL NUMBER IDENTIFIER
control field FlBoTFG
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220509193106.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr |||||||||||
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200724s2021 si a ob 000 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency OCoLC-P
Language of cataloging eng
Description conventions rda
-- pn
Transcribing agency OCoLC-P
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781003045410
-- (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1003045413
-- (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781000067392
-- (electronic bk. : Mobipocket)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1000067394
-- (electronic bk. : Mobipocket)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781000067385
-- (electronic bk. : PDF)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1000067386
-- (electronic bk. : PDF)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781000067378
-- electronic publication
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1000067378
-- electronic publication
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781000067354
-- electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1000067351
-- electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781000067361
-- Mobipocket electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 100006736X
-- Mobipocket electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781003045397
-- electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 1003045391
-- electronic book
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9789814877138
-- hardcover
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1201/9781003045397
Source of number or code doi
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)1202850119
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC-P)1202850119
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number TP248.E5
Item number P53 2021
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED
Subject category code subdivision 072000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 010000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI
Subject category code subdivision 013000
Source bisacsh
072 #7 - SUBJECT CATEGORY CODE
Subject category code MQP
Source bicssc
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 660.634
Edition number 23
245 00 - TITLE STATEMENT
Title Pharmaceutical biocatalysis :
Remainder of title important emzymes, novel targets, and therapies /
Statement of responsibility, etc edited by Peter Grunwald.
264 #1 -
-- Singapore :
-- Jenny Stanford Publishing,
-- [2021]
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource :
Other physical details illustrations (black and white, and colour).
336 ## -
-- text
-- rdacontent
336 ## -
-- still image
-- rdacontent
337 ## -
-- computer
-- rdamedia
338 ## -
-- online resource
-- rdacarrier
490 0# - SERIES STATEMENT
Series statement Jenny Stanford series on biocatalysis ;
Volume number/sequential designation volume 6
520 ## - SUMMARY, ETC.
Summary, etc This volume of Pharmaceutical Biocatalysis starts with a discussion on the importance of biocatalytic synthesis approaches for a sustainable and environmentally friendly production of pharmaceuticals and active pharmaceutical ingredients. Among the enzymes discussed in detail with respect to their pharmaceutical relevance are cyclic nucleotide phosphodiesterases playing an important role in modulating signal transduction in various cell types; human DOPA decarboxylase, related to Parkinson's disease and aromatic amino acid decarboxylase deficiency; and phospholipase D enzymes as drug targets. Isocitrate dehydrogenase 1 and 2 mutations are novel therapeutic targets in acute myeloid leukemia. An additional chapter is devoted to the use of enzymes for prodrug activation in cancer therapy. The other topics include small-molecule inhibitors targeting receptor tyrosine kinases in cancer, -Lactams and related compounds as antibacterials, non-vitamin K oral anticoagulants for the treatment of thromboembolic diseases, and the molecular mechanisms for statin pleiotropy and its clinical relevance in cardiovascular diseases. The last chapter is a review of lysosomal storage disorders with an overview of approved drugs for treating these disorders by enzyme replacement therapy.
588 ## -
-- OCLC-licensed vendor bibliographic record.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Enzymes
General subdivision Industrial applications.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biocatalysis.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmaceutical chemistry.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element MEDICAL / Pharmacy
Source of heading or term bisacsh
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element SCIENCE / Biotechnology
Source of heading or term bisacsh
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element SCIENCE / Chemistry / General
Source of heading or term bisacsh
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Grunwald, Peter,
Dates associated with a name 1941-
Relator term editor.
856 40 - ELECTRONIC LOCATION AND ACCESS
Materials specified Taylor & Francis
Uniform Resource Identifier https://www.taylorfrancis.com/books/9781003045397
856 40 - ELECTRONIC LOCATION AND ACCESS
Materials specified Taylor & Francis
Uniform Resource Identifier https://www.taylorfrancis.com/books/9781003045410
856 42 - ELECTRONIC LOCATION AND ACCESS
Materials specified OCLC metadata license agreement
Uniform Resource Identifier http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf

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