SuperMEN1 (Record no. 110445)

000 -LEADER
fixed length control field 03663nam a22004335i 4500
001 - CONTROL NUMBER
control field 978-1-4419-1664-8
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220084506.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100728s2010 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781441916648
-- 978-1-4419-1664-8
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4419-1664-8
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number R-RZ
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBGR
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED000000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Balogh, Katalin.
Relator term editor.
245 10 - TITLE STATEMENT
Title SuperMEN1
Medium [electronic resource] :
Remainder of title Pituitary, Parathyroid and Pancreas /
Statement of responsibility, etc edited by Katalin Balogh, Attila Patocs.
264 #1 -
-- New York, NY :
-- Springer New York,
-- 2010.
300 ## - PHYSICAL DESCRIPTION
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Advances in Experimental Medicine and Biology,
International Standard Serial Number 0065-2598 ;
Volume number/sequential designation 668
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note MEN1 Clinical Background -- Genetic Background of MEN1: From Genetic Homogeneity to Functional Diversity -- Menin: The Protein Behind the MEN1 Syndrome -- Cellular Functions of Menin -- The Role of Menin in Hematopoiesis -- Role of Menin in Bone Development -- Activin, TGF-? and Menin in Pituitary Tumorigenesis -- The Role of Menin in Parathyroid Tumorigenesis -- Role of Menin in Neuroendocrine Tumorigenesis -- Adrenal Tumors in MEN1 Syndrome and the Role of Menin in Adrenal Tumorigenesis -- Functional Studies of Menin through Genetic Manipulation of the Men1 Homolog in Mice.
520 ## - SUMMARY, ETC.
Summary, etc The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. SuperMEN1, Pituitary, Parathyroid and Pancreas provides an up-to-date summary from clinical basics and latest follow-up guidelines to the most recent molecular findings in multiple endocrine neoplasia Type 1 syndrome. Articles have been assembled by acknowledged experts in their respective fields to provide current perspectives on the clinical and genetic backgrounds of this syndrome and to review carefully the latest discoveries concerning the possible functions and interactions of menin, the protein encoded by the MEN1 gene, including its possible role in cell cycle regulation, hematopoiesis, and bone development. The goal of this valume is also to present the most recent findings and the broadest aspects of the role of menin in tumorigenesis of the endocrine glands involved in MEN 1 syndrome (pituitary, parathyroid, endocrine pancreas and adrenal). The connection between the basic experimental and clinical points of view are highlighted through a discussion on animal models, which explores the field in both an inspiring and questioning manner with a focus on areas that remain to be clarified. Our goal was to bring together clinicians and basic researchers who represent a wide range of interests in this particular field of endocrine oncology. Presenting a comprehensive and current overview of basic experimental and clinical findings, this book can bring us closer to understanding endocrine tumorigenesis in multiple endocrine neoplasia Type 1.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine general.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Patocs, Attila.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781441916624
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Advances in Experimental Medicine and Biology,
-- 0065-2598 ;
Volume number/sequential designation 668
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4419-1664-8
912 ## -
-- ZDB-2-SBL

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