Footmarks of Innate Immunity in the Ovary and Cytokeratin-Positive Cells as Potential Dendritic Cells (Record no. 107115)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04644nam a22004815i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-642-16077-6 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220083748.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 101120s2011 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783642160776 |
| -- | 978-3-642-16077-6 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-642-16077-6 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RG133.5 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MFKC |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | HEA039060 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.6 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Spanel-Borowski, Katharina. |
| Relator term | author. |
| 245 10 - TITLE STATEMENT | |
| Title | Footmarks of Innate Immunity in the Ovary and Cytokeratin-Positive Cells as Potential Dendritic Cells |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | by Katharina Spanel-Borowski. |
| 264 #1 - | |
| -- | Berlin, Heidelberg : |
| -- | Springer Berlin Heidelberg, |
| -- | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XV, 110p. 33 illus., 22 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in Anatomy, Embryology and Cell Biology, |
| International Standard Serial Number | 0301-5556 ; |
| Volume number/sequential designation | 209 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1 Background -- 1.1 Innate Immunity, Toll-like Receptors (TLR), and Danger Signals 1.2 The Ovary, Tissue Remodelling, and Immune Privilege -- 1.3 Design -- 2 Material and Methods -- 2.1 Cyclic and Superovulated Ovaries from Rats, Hamsters, Rabbits as well as Canine, Bovine and Human Ovaries -- 2.1.1 Fibrinolytic Activity and Implants on the Chick Chorioallantois Membrane (CAM) -- 2.1.2 Fixation, Staining and Counting Ovarian Structures -- 2.2 Cell Culture Subtypes from Follicles Derived from Patients Under in Vitro Fertilization Therapy -- 2.3 Cell Culture Subtypes from Bovine Corpus Luteum (CL) and Characterization -- 3 Footmarks of Innate Immunity -- 3.1 The Complement System as Danger Sensor in General and in the Ovary -- 3.2 Mild Danger with Mild Response -- 3.2.1 Implantation of the Ovary into the CAM -- 3.2.2 Follicular Atresia -- 3.3 Moderate Danger by Preovulatory Follicle Rupture and Acute Inflammation with Eosinophils -- 3.3.1 Recruitment of Eosinophils and Substance P-Like Expression -- 3.4 Severe Danger in Superovulated Ovaries with Intra-Ovarian Oocyte Release and Thrombus Formation -- 4 Cytokeratin-Positive (CK+) cell as Potential Dendritic Cells -- 4.1 Dendritic cells, the TLR System in General and in the Ovary -- 4.2 Localisation of CK+ Cells in the Intact Ovary -- 4.2.1 Follicles in Foetal and Adult Ovaries -- 4.2.2 Corpus Luteum -- 5 Characterization of Isolated CK+ Cells -- 5.1 CK+ Cells from Preovulatory Follicles with TLR4 Expression -- 5.2 CK+ Cells from CL in Comparison to CK-Negative (CK-) Cells -- 5.2.1 Effects of Interferon-gamma on CK+ Cells from the CL Compared to CK- Cells and to Surface Epithelial Cells -- 5.2.2 Reflections on Quality of the CK+ Type 1 and Similarity with the Type 5 -- 6 Working Hypothesis and Challenges -- 7 Clinical Perspectives -- 8 Concluding Summary and Remarks -- References -- Subject index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | The cyclic ovary can be seen as a site of tissue damage, repair and precisely controlled tissue homeostasis, as long ovulation and luteolysis can be compared with acute and chronic inflammation. Innate immunity appears to be a powerful force in the endocrine system, representing a novel concept. In this monograph, remarkable evidence is given for the immune-privileged ovary being an implant on the chicken chorioallantoic membrane with an areactive mesenchyme. Mild to severe tissue damages due to follicular atresia, follicular rupture, or intraovarian oocyte release do no lasting harm. The most exciting part relates to the analysis of cytokeratin-positive (CK+) cells, comparing the fate mapping of this cell type from the fetal ovary to the adult organ. Findings on toll-like receptor 4 regulation and interferon-gamma-dependent positive effects indicate that CK+ cells from human preovulatory follicles and bovine corpora lutea have similarities with nonlymphoid dendritic cells, a discovery that has the makings of a top story in basic and clinical research on the ovary. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human physiology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Reproductive Medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine & Public Health. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Reproductive Medicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Human Physiology. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Immunology. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783642160769 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in Anatomy, Embryology and Cell Biology, |
| -- | 0301-5556 ; |
| Volume number/sequential designation | 209 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-642-16077-6 |
| 912 ## - | |
| -- | ZDB-2-SME |
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