Drug Product Development for the Back of the Eye (Record no. 106155)

000 -LEADER
fixed length control field 05290nam a22004935i 4500
001 - CONTROL NUMBER
control field 978-1-4419-9920-7
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083731.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110725s2011 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781441999207
-- 978-1-4419-9920-7
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4419-9920-7
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RM1-950
072 #7 - SUBJECT CATEGORY CODE
Subject category code MMG
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED071000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Kompella, Uday B.
Relator term editor.
245 10 - TITLE STATEMENT
Title Drug Product Development for the Back of the Eye
Medium [electronic resource] /
Statement of responsibility, etc edited by Uday B. Kompella, Henry F. Edelhauser.
264 #1 -
-- Boston, MA :
-- Springer US,
-- 2011.
300 ## - PHYSICAL DESCRIPTION
Extent XII, 592 p.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement AAPS Advances in the Pharmaceutical Sciences Series,
International Standard Serial Number 2210-7371 ;
Volume number/sequential designation 2
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Selection of Drug Delivery Approaches for the Back of the Eye: Opportunities and Unmet Needs -- Microdialysis for Vitreal Pharmacokinetics -- Fluorophotometry for Pharmacokinetic Assessment -- Systemic Route for Retinal Drug Delivery: Role of the Blood-Retinal Barrier -- Topical Drug Delivery to the Back of the Eye -- Principles of Retinal Drug Delivery from Within the Vitreous -- Transscleral Drug Delivery -- Suprachoroidal and Intrascleral Drug Delivery -- Advances in Biodegradable Ocular Drug Delivery Systems -- Microparticles as Drug Delivery Systems for the Back of the Eye -- Nanotechnology and Nanoparticles -- Hydrogels for Ocular Posterior Segment Drug Delivery -- Refillable Devices for Therapy of Ophthalmic Diseases -- Targeted Drug Delivery to the Eye Enabled by Microneedles -- Ocular Iontophoresis -- Drug and Gene Therapy Mediated by Physical Methods -- Protein Drug Delivery and Formulation Development -- Drug Suspension Development for the Back of the Eye -- Regulatory Considerations in Product Development for Back of the Eye -- Clinical Endpoints for Back of the Eye Diseases -- Druggable Targets and Therapeutic Agents for Disorders of the Back of the Eye -- Development of Bile Acids as Anti-Apoptotic and Neuroprotective Agents in Treatment of Ocular Disease.
520 ## - SUMMARY, ETC.
Summary, etc This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Clinical endpoints and regulatory path to drug product development Emerging and existing drugs and drug targets   Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering.   Uday B. Kompella, Ph.D., Professor of Pharmaceutical Sciences & Ophthalmology, University of Colorado, developed functionalized nanoparticles, nanoporous microparticles, microparticles, injectable implants, dendrimers, liposomes, and in situ forming gels for the eye. He is a Fellow of the American Association of Pharmaceutical Scientists (2005) and the Association for Research in Vision and Ophthalmology (2010). He received Distinguished Scientist (2006) Award from the University of Nebraska.   Henry F. Edelhauser, Ph.D., Professor of Ophthalmology, Emory University, made pioneering contributions towards transcorneal, transscleral, and suprachoroidal drug delivery to the eye. He is a recipient of the Castroviejo Medal and the Alcon Research Award (1999), American Academy of Ophthalmology Senior Achievement Award (2000), and the Procter Medal (2005) for his outstanding ophthalmic translational research. He served as the president of the Association for Research in Vision and Ophthalmology (1990-91).
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Toxicology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmaceutical technology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Ophthalmology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmacology/Toxicology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Ophthalmology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Pharmaceutical Sciences/Technology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Edelhauser, Henry F.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781441999191
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title AAPS Advances in the Pharmaceutical Sciences Series,
-- 2210-7371 ;
Volume number/sequential designation 2
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4419-9920-7
912 ## -
-- ZDB-2-SBL

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