Targeted Learning (Record no. 106122)

000 -LEADER
fixed length control field 04984nam a22004695i 4500
001 - CONTROL NUMBER
control field 978-1-4419-9782-1
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083730.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 110616s2011 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781441997821
-- 978-1-4419-9782-1
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4419-9782-1
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QA276-280
072 #7 - SUBJECT CATEGORY CODE
Subject category code PBT
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MAT029000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 519.5
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name van der Laan, Mark J.
Relator term author.
245 10 - TITLE STATEMENT
Title Targeted Learning
Medium [electronic resource] :
Remainder of title Causal Inference for Observational and Experimental Data /
Statement of responsibility, etc by Mark J. van der Laan, Sherri Rose.
264 #1 -
-- New York, NY :
-- Springer New York,
-- 2011.
300 ## - PHYSICAL DESCRIPTION
Extent LXXII, 628 p.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
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-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Springer Series in Statistics,
International Standard Serial Number 0172-7397
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Models, Inference, and Truth -- The Open Problem -- Defining the Model and Parameter -- Super Learning -- Introduction to TMLE -- Understanding TMLE -- Why TMLE? -- Bounded Continuous Outcomes -- Direct Effects and Effect Among the Treated -- Marginal Structural Models -- Positivity -- Robust Analysis of RCTs Using Generalized Linear Models -- Targeted ANCOVA Estimator in RCTs -- Independent Case-Control Studies -- Why Match? Matched Case-Control Studies -- Nested Case-Control Risk Score Prediction -- Super Learning for Right-Censored Data -- RCTs with Time-to-Event Outcomes -- RCTs with Time-to-Event Outcomes and Effect Modification Parameters -- C-TMLE of an Additive Point Treatment Effect -- C-TMLE for Time-to-Event Outcomes -- Propensity-Score-Based Estimators and C-TMLE -- Targeted Methods for Biomarker Discovery -- Finding Quantitative Trait Loci Genes -- Case Study: Longitudinal HIV Cohort Data -- Probability of Success of an In Vitro Fertilization Program -- Individualized Antiretroviral Initiation Rules -- Cross-Validated Targeted Minimum-Loss-Based Estimation -- Targeted Bayesian Learning -- TMLE in Adaptive Group Sequential Covariate Adjusted RCTs -- Foundations of TMLE -- Introduction to R Code Implementation.
520 ## - SUMMARY, ETC.
Summary, etc The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest.   This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies. "Targeted Learning, by Mark J. van der Laan and Sherri Rose, fills a much needed gap in statistical and causal inference. It protects us from wasting computational, analytical, and data resources on irrelevant aspects of a problem and teaches us how to focus on what is relevant – answering questions that researchers truly care about." -Judea Pearl, Computer Science Department, University of California, Los Angeles "In summary, this book should be on the shelf of every investigator who conducts observational research and randomized controlled trials. The concepts and methodology are foundational for causal inference and at the same time stay true to what the data at hand can say about the questions that motivate their collection." -Ira B. Tager, Division of Epidemiology, University of California, Berkeley
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Statistics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Mathematical statistics.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Statistics.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Statistical Theory and Methods.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Public Health/Gesundheitswesen.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Statistics for Life Sciences, Medicine, Health Sciences.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rose, Sherri.
Relator term author.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781441997814
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Springer Series in Statistics,
-- 0172-7397
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4419-9782-1
912 ## -
-- ZDB-2-SMA

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