Central Nervous System Metastasis, the Biological Basis and Clinical Considerations (Record no. 104854)

000 -LEADER
fixed length control field 03364nam a22005055i 4500
001 - CONTROL NUMBER
control field 978-94-007-5291-7
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083348.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 121230s2012 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789400752917
-- 978-94-007-5291-7
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-94-007-5291-7
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC261-271
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJCL
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED062000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 614.5999
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Palmieri, Diane.
Relator term editor.
245 10 - TITLE STATEMENT
Title Central Nervous System Metastasis, the Biological Basis and Clinical Considerations
Medium [electronic resource] /
Statement of responsibility, etc edited by Diane Palmieri.
264 #1 -
-- Dordrecht :
-- Springer Netherlands :
-- Imprint: Springer,
-- 2012.
300 ## - PHYSICAL DESCRIPTION
Extent XI, 226 p. 32 illus., 27 illus. in color.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Cancer Metastasis - Biology and Treatment,
International Standard Serial Number 1568-2102 ;
Volume number/sequential designation 18
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Preface -- List of Contributors -- 1 An Introduction to Brain Metastasis -- 2 The Molecular Biology of Brain Metastasis -- 3 The Brain Microenvironment -- 4 Vascular permeability within brain metastases -- 5 Imaging Experimental Brain Metastases -- 6 Possibilities of Targeted Therapies for Brain Metastasis -- 7  Surgery for Brain Metastasis -- 8  Is There A Role for Systemic Chemotherapy in the Treatment of Brain Metastases? -- 9  Radiation Therapy of CNS Metastases -- 10  Leptomeningeal Metastasis -- 11 Quality of Life in CNS Metastasis -- Index.
520 ## - SUMMARY, ETC.
Summary, etc This volume covers what is known regarding the natural history, basic biology, and clinical aspects, including imaging and treatment, of CNS metastasis. Three chapters cover the biology of the brain and brain metastases: molecular biology, includes what is known about specific genes/proteins involved in the process of metastasis and model systems to study brain metastasis; brain microenvironment, focuses on the resident cells of the microenvironment and their role in CNS metastasis; and the blood-brain barrier, includes a discussion of permeability with respect to brain metastases. A discussion of experimental imaging covers both the biology of brain metastasis from an imaging perspective and the use of imaging techniques to study brain metastases. The three clinical chapters discuss treatment options of surgery, chemotherapy, and radiation. The potential for novel targeted therapies is also addressed. Because of the uniqueness of the disease, leptomeningeal metastasis is discussed separately. The last chapter is devoted to quality of life issues associated with CNS metastasis.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oncology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurosciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Radiology, Medical.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer Research.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Neurosciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oncology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Imaging / Radiology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine general.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9789400752900
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Cancer Metastasis - Biology and Treatment,
-- 1568-2102 ;
Volume number/sequential designation 18
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-94-007-5291-7
912 ## -
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