Aging Research in Yeast (Record no. 104514)

000 -LEADER
fixed length control field 04016nam a22005415i 4500
001 - CONTROL NUMBER
control field 978-94-007-2561-4
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140220083342.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 111117s2012 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789400725614
-- 978-94-007-2561-4
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-94-007-2561-4
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH301-705
072 #7 - SUBJECT CATEGORY CODE
Subject category code PSA
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code SCI086000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 570
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Breitenbach, Michael.
Relator term editor.
245 10 - TITLE STATEMENT
Title Aging Research in Yeast
Medium [electronic resource] /
Statement of responsibility, etc edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun.
264 #1 -
-- Dordrecht :
-- Springer Netherlands,
-- 2012.
300 ## - PHYSICAL DESCRIPTION
Extent XII, 368 p.
Other physical details online resource.
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
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347 ## -
-- text file
-- PDF
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490 1# - SERIES STATEMENT
Series statement Subcellular Biochemistry,
International Standard Serial Number 0306-0225 ;
Volume number/sequential designation 57
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note 1. Preface and Introduction to Aging research in Yeast -- 2.Oxidative stresses and ageing -- 3.The role of Mitochondria in the aging processes of yeast -- 4.The Retrograde Response and Other Pathways of Interorganelle Communication in Yeast Replicative Aging -- 5. Chronological Aging in Saccharomyces cerevisiae -- 6. Still waters run deep: Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- 7. Maximising the yeast chronological lifespan -- 8.Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae -- 9. DNA damage and DNA replication stress in yeast models of aging -- 10.Yeast aging and apoptosis.-11. Cellular homeostasis in fungi: Impact on the aging process -- 12.Genome-wide analysis of yeast aging -- 13. Genetic Approaches to Aging in Budding and Fission Yeasts: New Connections and New Opportunities -- 14. Evolution of asymmetric damage segregation: a modelling approach.-15. Cellular ageing and the actin cytoskeleton.
520 ## - SUMMARY, ETC.
Summary, etc This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life sciences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Geriatrics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cytology.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Microbiology.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life Sciences.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Life Sciences, general.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Geriatrics/Gerontology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cell Biology.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Apoptosis.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Oxidative Stress.
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Microbiology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jazwinski, S. Michal.
Relator term editor.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Laun, Peter.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9789400725607
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Subcellular Biochemistry,
-- 0306-0225 ;
Volume number/sequential designation 57
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-94-007-2561-4
912 ## -
-- ZDB-2-SBL

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