Matrix Metalloproteinase Inhibitors (Record no. 101732)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03011nam a22004335i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-3-0348-0364-9 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220083254.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120404s2012 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783034803649 |
| -- | 978-3-0348-0364-9 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-3-0348-0364-9 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC321-580 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED057000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.8 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gupta, Satya Prakash. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Matrix Metalloproteinase Inhibitors |
| Medium | [electronic resource] : |
| Remainder of title | Specificity of Binding and Structure-Activity Relationships / |
| Statement of responsibility, etc | edited by Satya Prakash Gupta. |
| 264 #1 - | |
| -- | Basel : |
| -- | Springer Basel, |
| -- | 2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | X, 285p. 184 illus., 11 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Experientia Supplementum, |
| International Standard Serial Number | 1023-294X ; |
| Volume number/sequential designation | 103 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Matrix Metalloproteinases -- Specificity of Binding with Matrix Metalloproteinases -- The Gelatinases and Their Inhibitors: The Structure–Activity Relationships -- Advances in Studies on Collagenase Inhibitors -- Hydroxamic Acids as Matrix Metalloproteinase Inhibitors -- Quantitative Structure–Activity Relationship Studies on Sulfonamide-Based MMP Inhibitors -- Matrix Metalloproteinase Inhibitors as Investigative Tools in the Pathogenesis and Management of Vascular Disease. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9783034803632 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Experientia Supplementum, |
| -- | 1023-294X ; |
| Volume number/sequential designation | 103 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-3-0348-0364-9 |
| 912 ## - | |
| -- | ZDB-2-SBL |
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