Translational Stroke Research (Record no. 100582)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05942nam a22004695i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-1-4419-9530-8 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20140220083234.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120322s2012 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781441995308 |
| -- | 978-1-4419-9530-8 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4419-9530-8 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC321-580 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSAN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED057000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 612.8 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Lapchak, Paul A. |
| Relator term | editor. |
| 245 10 - TITLE STATEMENT | |
| Title | Translational Stroke Research |
| Medium | [electronic resource] : |
| Remainder of title | From Target Selection to Clinical Trials / |
| Statement of responsibility, etc | edited by Paul A. Lapchak, John H. Zhang. |
| 264 #1 - | |
| -- | New York, NY : |
| -- | Springer New York : |
| -- | Imprint: Springer, |
| -- | 2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XXIV, 923 p. 162 illus., 107 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Springer Series in Translational Stroke Research |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Vascular Targets For Ischemic Stroke Treatment -- Identifying Vascular Targets to Treat Hemorrhagic Stroke -- Experimental Platforms For Assessing White Matter Pathophysiology In Stroke -- Neuroprotection in Stroke -- Protein Aggregation And Multiple Organelle Damage After Brain Ischemia -- Antioxidants And Stroke. Success And Pitfalls -- Caspase-Independent Stroke Targets -- Hypoxia-Inducible Factor: A New Hope To Counteract Stroke -- Thrombin in Ischemic Stroke Targeting -- Toll-Like Receptor Agonists As Antecedent Therapy For Ischemic Brain Injury: Advancing Preclinical Studies To The Nonhuman Primate -- Angiogenesis and Arteriogenesis As Stroke Targets -- Hematopoietic Growth Factor Family For Stroke Drug Development -- Soluble Epoxide Hydrolase As A Stroke Target -- Membrane Potential As Stroke Target -- Hypothermia To Identify Therapeutic Targets For Stroke Treatment -- Stroke Preconditioning To Identify Endogenous Protective Or Regenerative Mechanisms -- MicroRNAs in Ischemic Brain: The Fine-tuning Specialists and Novel Therapeutic Targets -- Neuroglobin: A Novel Target For Endogenous Neuroprotection -- Characterization Of Novel Neuroprotective Lipid Analogues For The Treatment Of Stroke -- Na+/H+ Exchangers As Therapeutic Targets For Cerebral Ischemia -- Iron as a therapeutic target in intracerebral hemorrhage: Preclinical testing of deferoxamine -- Overcoming Barriers To Translation From Experimental Stroke Models. Animal Models Of Stroke For Preclinical Drug Development: A Comparative Study Of Flavonols For Cytoprotection -- Clinical Relevance In A Translational Rodent Model Of Acute Ischemic Stroke: Incorporating The Biological Variability Of Spontaneous Recanalization -- A Clinically Relevant Rabbit Embolic Stroke Model For Acute Ischemic Stroke Therapy Development: Mechanisms & Targets -- Animal Models of Intracranial Aneurysm for treatment -- Animal Models of SAH and Their Translation to Clinical SAH -- ADME (Absorption, Distribution, Metabolism, Excretion) - The Real Meaning - Avoiding Disaster and Maintaining Efficacy for Preclinical Candidates -- CeeTox Analysis to De-risk Drug Development: The Three Antioxidants (NXY-059, RADICUT and STAZN) -- Site-Specific, Sustained-Release Drug Delivery for Subarachnoid Hemorrhage -- Therapeutic Potential of Intranasal Delivery of Drugs and Cells for Stroke and other Neurological Diseases -- High-Dose Albumin For Neuroprotection In Acute Ischemic Stroke: From Basic Investigations To Multicenter Clinical Trial -- The Translation Procedure Of Low-Level Laser Therapy In Acute Ischemic Stroke- A Non-Pharmaceutics Noninvasive Method -- Use Of Microbubbles In Acute Stroke -- Combination of High-Intensity Focused Ultrasound and Microbubbles for Stroke Treatment -- Cellular Therapy for Ischemic Stroke -- Clinical Trial Design and Repair-Based Therapies after Stroke -- A Critical Review of Stroke Trial Analytical Methodology: Outcome Measures, Study Design and Correction for Imbalances -- Metabolic Imaging in Translational Stroke Research -- Computational Analysis: A bridge to translational stroke treatment -- Innovations in stroke clinical trial design. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Translational Stroke Research: From Target Selection to Clinical Trials is part of “Springer Series in Translational Stroke Research.” Forty-three chapters from leading stroke research groups around the world select future targets and methods for stroke management such as the vasculature and white matter, protein aggregation, neuroglobin, microRNAs, oxidation, soluble epoxide hydrolase, apoptosis, hypoxia-inducible factors, thrombin, toll-like receptor, angiogenesis, membrane potentials and pumps. The book discusses methods to regulate brain temperature and the use of preconditioning in stroke. It also presents new areas of research emphasizing restoration of function with growth factors and stem cells. It provides multiple animal models of both ischemic and hemorrhagic stroke in order to translate basic preclinical findings to clinical trials with de-risking issues, therapy delivery methods such as sustained-release and intranasal delivery, and potential therapies including cell therapies, albumin, transcranial laser, microbubbles, and ultrasound. Finally, it debates clinical trial design for analytical methodology, imaging, computation, and innovations. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurobiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedicine. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurosciences. |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Neurobiology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, John H. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9781441995292 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Springer Series in Translational Stroke Research |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://dx.doi.org/10.1007/978-1-4419-9530-8 |
| 912 ## - | |
| -- | ZDB-2-SBL |
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